Mianserin hydrochloride (Org GB 94) in the treatment of obsessional states

Nine patients with severe primary obsessional illness were treated with mianserin hydrochloride (Org GB 94), in a dose increasing to 20 mg three times daily, for 4 weeks. Six patients improved as assessed by a physician's global rating of improvement. The symptoms on a side-effects check list were less marked during treatment than they had been during the pre-treatment drug-free period.