Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

PhenoDB: an integrated client/server database for linkage and population genetics

K H Cheung1, P Nadkarni, S Silverstein

  • 1Center for Medical Informatics, Yale University School of Medicine, New Haven, Connecticut, 06510, USA.

Computers and Biomedical Research, an International Journal
|August 1, 1996
PubMed
Summary

PhenoDB is a new database application designed for population and linkage genetics research. It simplifies managing and analyzing genetic marker data for populations and pedigrees, enhancing genetic studies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Yuan-Hu Zhi Tong Prescription Mitigates Tau Pathology and Alleviates Memory Deficiency in the Preclinical Models of Alzheimer's Disease.

Frontiers in pharmacology·2020
Same author

Variability in nuclear DNA among nonhuman primates: Application of molecular genetic techniques to intra- and inter-species genetic analyses.

American journal of primatology·2020
Same author

MAPlex - A massively parallel sequencing ancestry analysis multiplex for Asia-Pacific populations.

Forensic science international. Genetics·2019
Same author

THE ROLE OF GENETIC DRIFT IN THE DIFFERENTIATION OF ICELANDIC AND NORWEGIAN CATTLE.

Evolution; international journal of organic evolution·2017
Same author

Relaxation effect of a novel Danshensu/tetramethylpyrazine derivative on rat mesenteric arteries.

European journal of pharmacology·2015
Same author

Adrenomedullin increases the short-circuit current in the mouse seminal vesicle: actions on chloride secretion.

Biology of reproduction·2014

Area of Science:

  • Genetics
  • Bioinformatics
  • Computational Biology

Background:

  • Population and linkage genetics research requires robust data management and analysis tools.
  • Existing tools may lack comprehensive features for handling large genetic datasets and complex analyses.

Purpose of the Study:

  • To introduce PhenoDB, an Internet-accessible client/server database application.
  • To provide efficient data management and analysis capabilities for population and linkage genetics.

Main Methods:

  • Developed a client/server database application named PhenoDB.
  • Implemented interactive data validation during entry and editing.
  • Enabled data export/import with common genetic analysis program formats.
  • Integrated features for complex ad-hoc queries and project management reports.

Related Experiment Videos

Main Results:

  • PhenoDB efficiently manages and manipulates large genetic datasets (73 populations, 34 pedigrees, ~4200 individuals, ~80,000 typings).
  • The generic data format ensures compatibility with existing analysis programs (e.g., LIPED, Multipoint Linkage).
  • PhenoDB supports statistical summaries like allele frequencies and Hardy-Weinberg tests.

Conclusions:

  • PhenoDB offers a user-friendly graphical interface for complex genetic data tasks.
  • The application facilitates easier data management and analysis in population and linkage genetics.
  • PhenoDB enhances the efficiency and accessibility of genetic research data.