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Factor V Q 506 mutation in children with thrombosis

A Gurgey1, L Mesci, Y Renda

  • 1Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.

The factor V Leiden mutation in 12-children with thrombosis and in 20 controls was investigated. Five heterozygous individuals and 1 homozygous individual among the cases with thrombosis and 1 heterozygous individual among controls were found. Central nervous system thromboses were increased in children with the factor V mutation, associated with protein S deficiency.

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