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Somatostatin analogues and exocrine pancreatic secretion
1Department of Medicine and Gastroenterology, University of Bologna, St. Orsola Hospital, Italy.
Digestion
|January 1, 1996
Abstract:
Subcutaneous injection of 50 micrograms octreotide before a meal can almost totally prevent the increase in exocrine pancreatic secretions caused by the meal. Octreotide inhibits plasma amino acid uptake by pancreatic acinar cells, and thus synthesis of pancreatic enzymes. This effect has clinical potential.