Intervention in receptor tyrosine kinase-mediated pathways: recombinant antibody fusion proteins targeted to ErbB2

Tumor cell resistance against targeted therapeutics: the density of cultured glioma tumor cells enhances Stat3 activity and offers protection against the tyrosine kinase inhibitor canertinib.

MedChemComm·2018

O-GlcNAcylation of STAT5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies.

Leukemia·2017

c-Kit is required for growth and survival of the cells of origin of Brca1-mutation-associated breast cancer.

Oncogene·2011

Phosphoinositide 3-kinase signaling is critical for ErbB3-driven breast cancer cell motility and metastasis.

Oncogene·2011

Direction of the recognition specificity of cytotoxic T cells toward tumor cells by transduced, chimeric T-cell receptor genes.

Methods in molecular medicine·2011

Copine-III interacts with ErbB2 and promotes tumor cell migration.

Oncogene·2009

15-Hydroxyprostaglandin Dehydrogenase: A Key Metabolic Enzyme for Prostaglandins, 12-Hydroxyheptadecatrienoic Acid, and Resolvins.

Current topics in microbiology and immunology·2026

Resolution Failure in Multiple Sclerosis: Linking Lipid Mediators to Neuroinflammation and Disease Progression.

Current topics in microbiology and immunology·2026

Resolution Medicine: Steps to Uncovering the Specialized Pro-resolving Mediator Superfamily and Their Potent Functions in Resolving Inflammation.

Current topics in microbiology and immunology·2026

Dysregulated Resolution of Inflammation in Atherosclerosis: Mechanistic Insights and Therapeutic Opportunities.

Current topics in microbiology and immunology·2026

Resolution Pathways in the Context of Viral Infections.

Current topics in microbiology and immunology·2026

Stromal Niches Regulating Skin Immunity and Repair.

Current topics in microbiology and immunology·2026

Integrating a Tumor Size-Overall Survival Model Into a Spatial Quantitative Systems Pharmacology Framework for Antibody-Drug Conjugates in Non-Small Cell Lung Cancer.

CPT: pharmacometrics & systems pharmacology·2026

The Future of all-Comers Trials in the Era of Precision Oncology.

Clinical pharmacology and therapeutics·2026

Tumor Treating Fields Enhance Temozolomide-Associated Growth Suppression in Glioblastoma Cells and Patient-Derived Organoids Through Cell-Cycle Blockade, Apoptosis, and SMAD-Associated Signaling.

CNS neuroscience & therapeutics·2026

MyoD and Myogenin regulatory cascade is targeted by tumor signals to repress myogenesis in cancer cachexia.

The Biochemical journal·2026

Beyond the cerebrospinal fluid: Preclinical and clinical evidence on central nervous system penetration and functional activity of oral rapamycin (sirolimus).

Journal of Alzheimer's disease : JAD·2026

Conferone: Sources, Anticancer Mechanisms, and Potential in Overcoming Chemoresistance - A Comprehensive Review.

Current pharmaceutical design·2026

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Intervention in receptor tyrosine kinase-mediated pathways: recombinant antibody fusion proteins targeted to ErbB2

Related Concept Videos

Tumor cell resistance against targeted therapeutics: the density of cultured glioma tumor cells enhances Stat3 activity and offers protection against the tyrosine kinase inhibitor canertinib.

O-GlcNAcylation of STAT5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies.

c-Kit is required for growth and survival of the cells of origin of Brca1-mutation-associated breast cancer.

Phosphoinositide 3-kinase signaling is critical for ErbB3-driven breast cancer cell motility and metastasis.

Direction of the recognition specificity of cytotoxic T cells toward tumor cells by transduced, chimeric T-cell receptor genes.

Copine-III interacts with ErbB2 and promotes tumor cell migration.

15-Hydroxyprostaglandin Dehydrogenase: A Key Metabolic Enzyme for Prostaglandins, 12-Hydroxyheptadecatrienoic Acid, and Resolvins.

Resolution Failure in Multiple Sclerosis: Linking Lipid Mediators to Neuroinflammation and Disease Progression.

Resolution Medicine: Steps to Uncovering the Specialized Pro-resolving Mediator Superfamily and Their Potent Functions in Resolving Inflammation.

Dysregulated Resolution of Inflammation in Atherosclerosis: Mechanistic Insights and Therapeutic Opportunities.

Resolution Pathways in the Context of Viral Infections.

Stromal Niches Regulating Skin Immunity and Repair.

Integrating a Tumor Size-Overall Survival Model Into a Spatial Quantitative Systems Pharmacology Framework for Antibody-Drug Conjugates in Non-Small Cell Lung Cancer.

The Future of all-Comers Trials in the Era of Precision Oncology.

Tumor Treating Fields Enhance Temozolomide-Associated Growth Suppression in Glioblastoma Cells and Patient-Derived Organoids Through Cell-Cycle Blockade, Apoptosis, and SMAD-Associated Signaling.

MyoD and Myogenin regulatory cascade is targeted by tumor signals to repress myogenesis in cancer cachexia.

Beyond the cerebrospinal fluid: Preclinical and clinical evidence on central nervous system penetration and functional activity of oral rapamycin (sirolimus).

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Intervention in receptor tyrosine kinase-mediated pathways: recombinant antibody fusion proteins targeted to ErbB2

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