[Recent advances in laboratory approaches to hematologic disorders]

During recent years, there has been substantial advance in our knowledge of the etiology, pathogenesis, laboratory diagnosis, and management of hematologic disorders. In this symposium, the discussion includes the following six topics: (1) some problems of automatic blood cell analyzer and flow cytometer for the diagnostic use of hematologic disorders, (2) usefulness of fluorescence in situ hybridization techniques for the diagnosis of leukemias, (3) recent advance in pathogenesis and management of multiple myeloma, (4) usefulness of the thrombin-antithrombin III complex, plasmin-antiplasmin complex, and tissue factor activity for the diagnosis of disseminated intravascular coagulation syndrome, (5) detection of activated platelets, and (6) molecular diagnosis of hereditary coagulation disorders.