Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Findlay implantable two-stage centrifugal pump

P V Moulder1, I S Findlay, R M Zone

  • 1Louisiana State University, New Orleans, USA.

Artificial Organs
|June 1, 1996
PubMed
Summary

The novel Findlay centrifugal pump, featuring a two-stage mechanism, demonstrates low blood damage and efficient performance. This implantable device shows promise for ventricular assist applications.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Anti-HBs Immune Complex Levels: A Novel Marker of Hepatitis Flare Following Nucleos(t)ide Analog Withdrawal in HBeAg-negative Chronic Hepatitis B.

The Journal of infectious diseases·2025
Same author

Balancing Efficiency and Accuracy in Hepatitis C Rapid Antibody Testing: Insights From a Cluster Randomised Crossover Trial.

Journal of viral hepatitis·2025
Same author

Editorial: Ultralow HBsAg Levels and the Prediction of Cure in Chronic Hepatitis B.

Alimentary pharmacology & therapeutics·2025
Same author

New insights into the effects of ethylene on ABA catabolism, sweetening and dormancy in stored potato tubers.

Postharvest biology and technology·2021
Same author

Direct Measurement of Single-Molecule Ligand-Receptor Interactions.

The journal of physical chemistry. B·2020
Same author

Prevalence of baseline HCV NS5A resistance associated substitutions in genotype 1a, 1b and 3 infection in Australia.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology·2019

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Devices

Background:

  • Ventricular assist devices (VADs) are crucial for managing heart failure.
  • Improving VAD efficiency and minimizing blood damage are key research areas.

Purpose of the Study:

  • To evaluate the performance and hemocompatibility of the novel Findlay centrifugal pump.
  • To assess the suitability of the Findlay pump for ventricular assist applications.

Main Methods:

  • Fabrication and functional analysis of 26 prototype Findlay centrifugal pumps.
  • Hemolysis testing of six pumps over 3.5–5 hours.
  • Acute studies in 44 normal dogs using the pump in a ventricular assist system.

Main Results:

  • The pump utilizes a unique two-stage mechanism: a lift force pump followed by a shear force pump.

Related Experiment Videos

  • Demonstrated minimal hemolysis (3.5–5 h) and efficient water pumping (up to 10 L/min).
  • In canine studies, blood flow ranged from 1.2 to 4.5 L/min with acceptable hydraulic and mechanical efficiency.

    • Conclusions:

    • The Findlay centrifugal pump exhibits low blood damage and operates efficiently at acceptable speeds.
    • Its small size and implantable nature make it a promising candidate for VADs.
    • The two-stage design contributes to its overall effectiveness as a cardiovascular support device.