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Related Experiment Videos

Electrochemical detection in bioanalysis

P T Kissinger1

  • 1Bioanalytical Systems, Inc., West Lafayette, IN 47906, USA.

Journal of Pharmaceutical and Biomedical Analysis
|June 1, 1996
PubMed
Summary
This summary is machine-generated.

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This review explores amperometric electrochemical detectors for bioanalytical chemistry. It covers in-vivo sampling, chromatography, electrophoresis, and electrode materials for advanced applications.

Area of Science:

  • Bioanalytical Chemistry
  • Electrochemistry

Background:

  • Amperometric electrochemical detectors are crucial tools in bioanalytical chemistry.
  • Advancements in detector technology enable more sensitive and specific analyses.

Purpose of the Study:

  • To provide a comprehensive overview of current research on amperometric electrochemical detectors in bioanalytical chemistry.
  • To highlight key techniques and materials used in conjunction with these detectors.

Main Methods:

  • Review of current literature on amperometric electrochemical detection.
  • Discussion of various sampling techniques, separation methods, and detection strategies.

Main Results:

  • Integration of microdialysis and ultrafiltration for in-vivo sampling.

Related Experiment Videos

  • Application in microbore liquid chromatography and capillary electrophoresis.
  • Utilisation of post-column reactions (enzyme, photochemical, chemical) and electrochemiluminescence.
  • Development and use of thin-film electrode materials.

    • Conclusions:

    • Amperometric electrochemical detectors are versatile tools in bioanalytical chemistry.
    • Ongoing research focuses on improving sampling, separation, and detection methodologies.
    • Thin-film electrodes and advanced reaction techniques enhance analytical capabilities.