[The characteristics of lymphocyte membrane function in pyelonephritis patients]

Lipid, phospholipid and fattyacid spectrum of membranes of lymphocytes isolated from the peripheral blood of patients with pyelinephritis were studied. It has been established that in the active phase of the disease the ratio of certain lipidic and phospholipidic fractions gets changed, in the first place, those of free cholesterin, phospholipids, phosphatidilcholin, phosphatidilethanolamine. In the fattyacid spectrum, the content of oleic, linoleic and, in particular, arachidonic acid, has been noted to get reduced. The aforementioned changes may further secondary immunity deficiency the pyelonephritis course is associated with.