Related Experiment Videos
Younger age as a bad prognostic factor in patients with carcinoma of the cervix
J F Delaloye1, S Pampallona, P A Coucke
1Departement de Gynecologie et d'Obstetrique, Centre Hospitalier Universitaire, Vaudois, Switzerland.
Objective:
To verify the influence of age on the prognosis of cervix carcinoma.
Study Design:
Five hundred and sixty eight patients treated for a FIGO stage IB-IVA with radical irradiation in the Centre Hospitalier Universitaire Vaudois of Lausanne were subdivided according to the following age categories: < or = 45, 46-60, 61-69 and >70 years. Taking the 46-60 years age group as the reference, the hazard ratios (HR) of death and corresponding 95% confidence intervals (95% CI) were estimated by means of a Cox multivariate analysis.
Results:
The 5-year survival rates were, respectively, 57%, 67%, 60% and 45%. For the youngest women the risk of death was significantly increased (HR = 2.00, 95% CI [1.32-3.00]) and was even more accentuated in advanced stages.
Conclusion:
Age under 45 years is a bad prognostic factor in carcinoma of the cervix.