New method for breast cancer detection using TC-99m sestamibi scintimammography

The combination of breast examination and radiographic mammography (XRMM) are the established methods for breast cancer detection. However, XRMM lacks sensitivity and specificity in women with dense breasts, leading to false positive findings in 80% and false negative findings in 10% to 15% of the cases. Tc-99m Sestamibi (MIBI) scintimammography (SMM) is a new breast-imaging technique. This study shows that SMM has a positive predictive value of 83% and negative predictive value of 93%, which is similar to that reported by others. This supports other published reports that SMM is a potential excellent complimentary imaging technique to XRMM in improving the accuracy of breast cancer detection.