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Cloning and sequence analysis of a full-length cDNA of rat adrenodoxin
Y Sagara1, Y Watanabe, K Kawamura
1Department of Medical Biology, Kochi Medical School, Japan.
Biological & Pharmaceutical Bulletin
|January 1, 1996
Abstract:
A cDNA clone which covers the entire coding region for the precursor of adrenodoxin was isolated from a rat adrenal cDNA library. This precursor consists of amino-terminal 64 residues of extrapeptide for transport into mitochondria and the following 124 residues of mature peptide region. The amino acid sequence of rat mature adrenodoxin showed 85-98% homology with mouse, human, chicken, porcine, bovine and sheep counterparts, whereas that of the extrapeptide showed significantly lower values.