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Related Experiment Videos

Adjuvant analgesic agents

R K Portenoy1

  • 1Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

Hematology/Oncology Clinics of North America
|February 1, 1996
PubMed
Summary
This summary is machine-generated.

Adjuvant analgesics help manage cancer pain when opioids are insufficient or cause side effects. Clinicians need knowledge of these drugs and patient assessment for effective pain management.

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Area of Science:

  • Oncology
  • Pain Management
  • Pharmacology

Background:

  • Opioid therapy is standard for cancer pain but can lead to inadequate analgesia or side effects.
  • Comorbid conditions may also require specific treatments that adjuvant analgesics can address.
  • Adjuvant analgesics offer an alternative or supplementary approach to cancer pain management.

Purpose of the Study:

  • To review the role and considerations for using adjuvant analgesics in cancer pain management.
  • To emphasize the importance of balancing benefits against risks like polypharmacy.
  • To guide clinicians in selecting appropriate adjuvant analgesics based on patient assessment.

Main Methods:

  • Literature review of adjuvant analgesics in cancer pain.
  • Analysis of clinical scenarios for adjuvant analgesic use.

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  • Discussion of risk-benefit assessment and polypharmacy concerns.

    • Main Results:

    • Adjuvant analgesics are indicated when opioid therapy provides insufficient pain relief or intolerable side effects.
    • These agents can also manage comorbid symptoms contributing to overall pain.
    • Careful patient and pain syndrome assessment is crucial for optimal selection and use.

    Conclusions:

    • Adjuvant analgesics are valuable tools in the multimodal management of cancer pain.
    • Informed clinical decision-making requires a thorough understanding of available agents and patient-specific factors.
    • Balancing the benefits of improved analgesia against the risks of polypharmacy is essential.