Molecular recognition of saccharides using synthesized glycated surface active reagents

The molecular recognition of saccharides was studied using N-glycosides, glycated surface active reagents synthesized by the glycosyl reaction from alkylamines and monosaccharides. The alkylamines selected were octyl and dodecylamines because of their hydrophobicity. Glucose and mannose were selected as an energy saccharide and a structural saccharide, respectively. The synthesized glycated surface-active reagents were added as components of the carrier solution used for capillary electrophoresis, and the selective molecular recognition of saccharides was studied using several nitrogen-containing compounds. The migration times of the cationic forms of nitrogen-containing compounds were delayed by interaction with the N-glycosides. However, this system did not show clear selectivity between glucose and mannose.