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Published on: January 17, 2019
Perforated appendicitis and ectopic pregnancy following in-vitro fertilization
M A Akman1, E Katz, M D Damewood
1Department of Gynecology, Greater Baltimore Medical Center, Maryland 21204, USA.
Human Reproduction (Oxford, England)
|December 1, 1995
Summary
This case report details a rare instance of perforated appendicitis and ectopic pregnancy after in-vitro fertilization (IVF) and embryo transfer. Prompt intervention for appendicitis and methotrexate treatment for the ectopic pregnancy ensured patient survival and resolution.
Area of Science:
- Reproductive Medicine
- Surgical Gastroenterology
- Obstetrics and Gynecology
Background:
- In-vitro fertilization (IVF) and embryo transfer are advanced reproductive technologies.
- Ectopic pregnancy is a significant risk following assisted reproductive procedures.
- Appendicitis, while common, can present with severe complications like perforation.
Observation:
- A patient undergoing IVF experienced both perforated appendicitis and an ectopic pregnancy.
- The perforated appendicitis was diagnosed and treated urgently.
- The ectopic pregnancy was managed non-surgically.
Findings:
- Perforated appendicitis occurred coincidentally in the context of IVF and embryo transfer.
- Immediate surgical intervention for appendicitis was life-saving.
- Two doses of methotrexate effectively resolved the ectopic pregnancy.
Implications:
- This case highlights the importance of vigilant diagnosis for concurrent, potentially life-threatening conditions in patients undergoing assisted reproduction.
- It underscores the successful, albeit coincidental, management of both perforated appendicitis and ectopic pregnancy in a single patient.
- Reinforces the established efficacy of methotrexate for ectopic pregnancy resolution.
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