Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Postictal language dysfunction in patients with right or bilateral hemispheric language localization

M Privitera1, C Kohler, W Cahill

  • 1Department of Neurology, University of Cincinnati Medical Center 45267-0525, USA.

Epilepsia
|October 1, 1996
PubMed
Summary

Postictal language testing accurately identifies patients with non-left hemisphere language dominance. This method may help select patients for the intracarotid amobarbital test (IAT).

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

First Constraints on General Neutrino Interactions Based on KATRIN Data.

Physical review letters·2025
Same author

Accurate and reproducible whole-genome genotyping for bacterial genomic surveillance with Nanopore sequencing data.

Journal of clinical microbiology·2025
Same author

Magnetic resonance imaging and ultrasound examination in preoperative pelvic staging of early-stage cervical cancer: post-hoc analysis of SENTIX study.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2025
Same author

Parental conflict driven regulation of endosperm cellularization by a family of Auxin Response Factors.

Nature plants·2024
Same author

The impact of the COVID-19 pandemic on presentation of surgical disease in paediatric patients at a tertiary centre in Cape Town, South Africa.

South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie·2024
Same author

Influence of chemoradiation on the immune microenvironment of cervical cancer patients.

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]·2022

Area of Science:

  • Neurology
  • Neurosurgery
  • Epileptology

Background:

  • Temporal lobe complex partial seizures (TLCPS) originating from the language dominant hemisphere impair reading ability post-seizure.
  • Previous research established a pattern of impaired reading within 60 seconds of seizure end for left-hemisphere dominant seizures.

Purpose of the Study:

  • To determine if discordant postictal language testing patterns can identify patients with non-left hemisphere language dominance.
  • To assess the utility of postictal language testing in localizing language dominance.

Main Methods:

  • Video/EEG monitoring with a standardized reading test administered within 60 seconds of seizure cessation.
  • Inclusion criteria included successful postictal testing, >90% seizure reduction after anterior temporal lobectomy, and confirmed language localization via intracarotid amobarbital test (IAT) or cortical stimulation.

Related Experiment Videos

  • Analysis of 224 seizures from 64 patients.

    • Main Results:

    • Discordant postictal language patterns were observed in 90.9% of patients with non-left hemisphere language dominance (10/11).
    • These patterns were also noted in 28.3% of patients with left hemisphere dominance (15/53), with a p-value of 0.006.
    • The sensitivity and specificity for identifying non-left language dominance were 90.9% and 71.7%, respectively.

    Conclusions:

    • Postictal language testing is a valuable tool for accurately identifying patients with non-left hemisphere language dominance.
    • This testing may serve as a useful adjunct in selecting patients for further evaluation with the intracarotid amobarbital test (IAT).