Clinical outcome of patients evaluated with emergency centre myocardial perfusion SPET for unexplained chest pain

R E Stewart1, C Z Dickinson, I A Weissman

  • 1Department of Nuclear Medicine, William Beaumont Hospital, Royal Oak, MI, USA.

Insights

Emergency centre (EC) single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) effectively triaged patients with chest pain. Most discharged patients remained symptom-free, and none with normal MPI experienced adverse events.

Area of Science:

  • Cardiology
  • Nuclear Medicine
  • Emergency Medicine

Background:

  • Unexplained chest pain is a common emergency centre presentation.
  • Accurate and timely diagnosis is crucial for patient management and outcomes.
  • Myocardial perfusion imaging (MPI) plays a role in assessing cardiac ischemia.

Purpose of the Study:

  • To evaluate the clinical outcome of patients with unexplained chest pain.
  • To assess the utility of emergency centre (EC) single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) in triage.
  • To determine the safety and efficacy of EC-MPI for chest pain evaluation.

Main Methods:

  • Prospective assessment of 68 patients presenting with unexplained chest pain.
  • Triage decisions based on clinical presentation and EC SPECT MPI.
  • Follow-up at 9 months to assess clinical outcomes and symptom recurrence.

Main Results:

  • 63% (43/68) of patients were discharged directly from the EC based on clinical assessment and EC-MPI.
  • Of those discharged, 84% (36/43) remained symptom-free at 9-month follow-up.
  • No adverse clinical events were observed in patients with a completely normal EC-MPI result.

Conclusions:

  • EC SPECT MPI is a valuable tool for the safe and effective triage of patients with unexplained chest pain.
  • Normal EC-MPI results correlate with excellent short-term clinical outcomes and absence of adverse events.
  • This imaging modality can facilitate early discharge for a significant proportion of patients presenting with chest pain.

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