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Related Experiment Videos

Left ventricular mass regression early after aortic valve replacement

G T Christakis1, C D Joyner, C D Morgan

  • 1Division of Cardiovascular Surgery, Sunnybrook Health Science Centre, University of Toronto, Ontario, Canada.

The Annals of Thoracic Surgery
|October 1, 1996
PubMed
Summary

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Left ventricular mass regression starts early after aortic valve replacement, regardless of prosthesis type. This significant reduction in left ventricular mass index occurs within days of surgery.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Echocardiography

Background:

  • Left ventricular hypertrophy regression is a known benefit of aortic valve replacement.
  • The timing and prosthesis-type influence on early left ventricular mass regression are not well understood.

Purpose of the Study:

  • To investigate the earliest evidence of left ventricular mass regression post-aortic valve replacement.
  • To determine if prosthesis type affects early left ventricular mass regression.

Main Methods:

  • Transthoracic echocardiography measured left ventricular mass index in 57 patients undergoing isolated aortic valve replacement.
  • Measurements were taken preoperatively and before hospital discharge.

Main Results:

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  • A significant reduction in left ventricular mass index was observed (141.4 to 127.5 g/m², p=0.0005).
  • No significant differences in regression were found between mechanical bileaflet, stented tissue bioprostheses, and stentless porcine bioprostheses.
  • Conclusions:

    • Left ventricular mass regression begins early after aortic valve replacement.
    • The type of prosthesis implanted does not appear to influence the extent of early mass regression.