Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Real-time 3D dose calculation and display: a tool for plan optimization

J W Matthews1, F U Rosenberger, W R Bosch

  • 1Mallinckrodt Institute of Radiology, Washington University School of Medicine, Louis, MO, USA. jwm@castor.wustl.edu

International Journal of Radiation Oncology, Biology, Physics
|August 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Helical tomotherapy with simultaneous integrated boost dose painting for the treatment of synchronous primary cancers involving the head and neck.

The British journal of radiology·2014
Same author

Evaluation of hippocampus dose for patients undergoing intensity-modulated radiotherapy for nasopharyngeal carcinoma.

The British journal of radiology·2014
Same author

Clinical-dosimetric relationship between lacrimal gland dose and ocular toxicity after intensity-modulated radiotherapy for sinonasal tumours.

The British journal of radiology·2013
Same author

Intensity-modulated radiotherapy for nasopharyngeal carcinoma: improvement of the therapeutic ratio with helical tomotherapy vs segmental multileaf collimator-based techniques.

The British journal of radiology·2012
Same author

Changes in position and volume of lung cancer target volumes during stereotactic body radiotherapy (SBRT): is image guidance necessary?

Technology in cancer research & treatment·2011
Same author

Comparison of IMRT techniques in the radiotherapeutic management of head and neck cancer: is tomotherapy "better" than step-and-shoot IMRT?

Technology in cancer research & treatment·2011
Same journal

Local sinonasal and regional nodal effects of lymph node irradiation in a pilot study of dogs with naturally occurring sinonasal tumors.

International journal of radiation oncology, biology, physics·2026
Same journal

Cross-Institutional Validation of a novel LLM-Based Cardiac Event Extraction framework from Electronic Health Records.

International journal of radiation oncology, biology, physics·2026
Same journal

Cardiac Substructure Dosimetry and Major Adverse Cardiac Events After Breast Radiotherapy: A 12-Year Cohort Study with NTCP Modeling.

International journal of radiation oncology, biology, physics·2026
Same journal

Predictors of Medical Debt Sent to Collections after Radiotherapy.

International journal of radiation oncology, biology, physics·2026
Same journal

External Beam Radiotherapy Primes PDL1-Targeted Radionuclide Therapy in Preclinical Colorectal Cancer Model.

International journal of radiation oncology, biology, physics·2026
Same journal

Radiobiological characterization of 60 keV quasi-monoenergetic convergent photons.

International journal of radiation oncology, biology, physics·2026
See all related articles

Real-time dose calculation and display systems enable faster treatment plan optimization. Multiprocessor workstations make this practical for 3D conformal radiation therapy planning.

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Computational Imaging

Background:

  • Human optimization of radiation therapy plans is limited by slow feedback on parameter changes.
  • Computerized calculations offer precision but lack human pattern recognition.
  • A need exists for integrated systems providing rapid feedback for effective treatment planning.

Purpose of the Study:

  • To develop a real-time dose calculation and display system for immediate feedback during treatment plan optimization.
  • To enable experienced planners to adjust beam parameters based on immediate effectiveness indicators.
  • To utilize 3D visualization of dose distributions and anatomical structures for improved planning.

Main Methods:

  • Utilized multiprocessor workstations with tightly coupled calculation and display capabilities.

Related Experiment Videos

  • Ported existing dose calculation code to a shared-memory, multithreaded architecture.
  • Implemented real-time recalculation of 3D dose matrices and display updates.

    • Main Results:

    • Achieved <0.1s update times for 3D dose surface displays after beam parameter changes.
    • Demonstrated <0.1s calculation time for 64x64-pixel digitally reconstructed radiographs (DRRs).
    • Identified the need for additional features like automated aperture calculation for full clinical practicality.

    Conclusions:

    • Real-time plan optimization using multiprocessor workstations is feasible for 3D planning.
    • Parallel processing enhances 3D conformal radiation therapy optimization when combined with objective ranking.
    • Shared-memory multiprocessor workstations offer ease of programming and performance advantages for future development.