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Scleromyxedema with myopathy and hyperthyroidism

D Van Linthoudt¹, H R Schumacher, S Algeo

¹Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, USA.

The Journal of Rheumatology

|July 1, 1996

Summary

This study details a rare case of scleromyxedema in a 62-year-old woman, presenting with skin lesions, dysphagia, and muscle weakness. The condition was associated with hyperthyroidism, highlighting a complex interplay between autoimmune skin disease and endocrine dysfunction.

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Area of Science:

Dermatology
Endocrinology
Neurology

Background:

Scleromyxedema is a rare connective tissue disease characterized by papular skin lesions and systemic involvement.
Muscle weakness and dysphagia can be presenting symptoms, suggesting potential neurological or muscular complications.
The association between scleromyxedema and hyperthyroidism is not well-established, necessitating further investigation.