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Regional enteritis complicating malignant lymphoma

W Veldman¹, M van Beek, J J Keuning

¹Department of Internal Medicine, St. Joseph Hospital, Veldhoven, Netherlands.

The Netherlands Journal of Medicine

|August 1, 1996

Summary

This summary is machine-generated.

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A patient achieved remission from non-Hodgkin's lymphoma with chemotherapy, but later developed Crohn's disease. This rare co-occurrence of lymphoma and inflammatory bowel disease lacks a clear explanation.

Area of Science:

Oncology
Gastroenterology
Immunology

Background:

Non-Hodgkin's lymphoma is a malignancy of lymphocytes.
Inflammatory bowel disease (IBD) encompasses chronic inflammatory conditions of the gastrointestinal tract, such as Crohn's disease.
The co-occurrence of IBD and lymphoma is infrequently reported.

Observation:

A patient presented with palpable lymph nodes indicative of non-Hodgkin's lymphoma.
Chemotherapy successfully induced complete remission of the lymphoma.
One year post-treatment, the patient developed symptoms of cramping abdominal pain, diarrhea, and bloody stools.

Findings:

The patient's gastrointestinal symptoms were diagnosed as Crohn's disease of the colon.
This case represents a rare instance of concurrent inflammatory bowel disease and malignant lymphoma.

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No established explanation currently exists for the simultaneous occurrence of these two conditions.

Implications:

This case highlights a rare clinical presentation requiring careful differential diagnosis.
Further research may be needed to explore potential shared etiologies or pathogenetic mechanisms between lymphoma and IBD.
Understanding this association could inform future diagnostic and therapeutic strategies for patients with either condition.