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Anti-emetic principles of Poria cocos
1Central Research Laboratory Kotaro Pharmaceutical Co. Ltd., Osaka, Japan.
Planta Medica
|December 1, 1995
Abstract:
The triterpenes isolated from P. cocos and their derivatives were examined for anti-emetic activity. Some of these triterpenes inhibited emetic action induced by oral administration of copper sulfate pentahydrate to leopard frog. The triterpenes having an exomethylene group at C-24 showed anti-emetic activity to frogs.