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Genetic epidemiology of the Mitsuda reaction in leprosy
M Feitosa1, H Krieger, I Borecki
1Departamento de Genética-Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Human Heredity
|January 1, 1996
Abstract:
This study comprised 544 nuclear families with 2,925 individuals tested for the Mitsuda reaction, from the Campinas region in Brazil. Segregation analyses suggest the segregation of a major gene (chi 2(1) = 0.07 - 0.07 = 0, p = 1), by failing to reject the hypothesis of Mendelian transmission and by rejecting the hypothesis of nontransmission of a major gene (chi 2(3) = 0.07 - 0.0 = 0.07, p > 0.99; chi 2(2) = 198.28 - 0.0 = 198.28, p < 0.0001).