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Related Experiment Videos

Heat contact urticaria--a case report

H S Chung1, K H Lee, J Y Ro

  • 1Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea.

Yonsei Medical Journal
|June 1, 1996
PubMed
Summary

Heat contact urticaria, a rare condition, causes localized wheals upon heat exposure. A case study found a 39°C threshold and successful treatment with heat desensitization and indomethacin.

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Area of Science:

  • Dermatology
  • Allergology
  • Immunology

Background:

  • Heat contact urticaria is a rare condition characterized by localized wheals upon heat exposure.
  • Symptoms manifest rapidly after contact and are transient.

Observation:

  • Symptoms manifested within 5 minutes of heat exposure, lasting 30-60 minutes, with no systemic involvement.
  • Experimental induction confirmed localized heat urticaria with a threshold temperature of 39°C.
  • Plasma levels of prostaglandin D2 and histamine were investigated before and after heat challenge.

Findings:

  • The patient demonstrated significant improvement with a combined treatment approach.
  • This treatment included desensitization through repeated heat exposure and the administration of indomethacin.

Implications:

  • This case highlights a potential therapeutic strategy for heat contact urticaria.
  • Further research into prostaglandin D2 and histamine pathways in heat urticaria is warranted.

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