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Updated: Aug 6, 2026

Assessing Cerebral Autoregulation via Oscillatory Lower Body Negative Pressure and Projection Pursuit Regression
Published on: December 10, 2014
Pelvic blood pooling of men and women during lower body negative pressure
1ML Lifeguard Equipment Limited, Clwyd, Wales, UK.
Introduction:
The objective of this study was to investigate possible gender differences in the hemodynamic responses of the lower body during lower body negative pressure (LBNP).
Methods:
In this study, 17 women (mean age = 56 yrs) and 15 men (mean age = 55 yrs) underwent a 15 min exposure to -50 mm Hg LBNP. A Beckman (BR-100) Impedance Plethysmograph was used to measure each subject's leg and pelvic blood flow and pooling during the LBNP test.
Results:
The women had an 83% greater increase in blood volume in the pelvic region than men as a result of the LBNP exposure. Women and men had similar increases in leg blood volume as a result of the 15 min exposure to -50 mm Hg. There was no significant gender difference in the decreased amount of blood flow to the leg or pelvic regions by the end of -50 mm Hg LBNP.
Conclusions:
These results demonstrate that women have greater blood pooling in the pelvic region compared to men when exposed to -50 mm Hg LBNP. These results should be considered when designing life-support equipment for men and women pilots and astronauts, especially the designing of anti-G and Space Shuttle re-entry garments.
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