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Treatment-resistant depression in children and adolescents
1Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.
The Psychiatric Clinics of North America
|June 1, 1996
Abstract:
Treatment resistance in depressed children and adolescents cannot yet be defined fully because of the paucity of controlled studies that demonstrate efficacy. Therefore, this article addresses several of the age-specific, developmental considerations that may impinge upon treatment response. Areas covered include familial-genetic, psychosocial, and neuroimaging studies in addition to a review of controlled studies to date.