Related Experiment Video
Updated: Aug 10, 2026

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock
Published on: November 3, 2023
Hypertensive crisis in children
1Department of Child Health, University of Missouri, Columbia 65212, USA.
Insights
Children with severe hypertension and organ damage need emergency treatment. Careful blood pressure reduction in an intensive care unit using intravenous medications is crucial to prevent serious complications.
Area of Science:
- Pediatrics
- Cardiology
- Nephrology
Background:
- Hypertensive emergencies in children can lead to severe, life-threatening complications, including central nervous system damage.
- Prompt recognition and management are essential to prevent long-term sequelae.
Purpose of the Study:
- To outline the appropriate management of hypertensive emergencies in pediatric patients.
- To emphasize the importance of controlled blood pressure reduction and monitoring.
Main Methods:
- Review of current guidelines and clinical practices for managing pediatric hypertensive emergencies.
- Focus on the use of intravenous medications for rapid and controlled blood pressure lowering.
- Emphasis on intensive care unit (ICU) management with continuous monitoring of vital organ function.
Main Results:
- Intravenous agents, such as nicardipine, sodium nitroprusside, or labetalol, are preferred for controlled blood pressure reduction in hypertensive emergencies.
- Treatment should aim to lower blood pressure sufficiently to mitigate toxicity without causing hypoperfusion.
- Oral agents are generally reserved for milder cases without evidence of end-organ damage.
Conclusions:
- Hypertensive emergencies in children require prompt, expert management, often in an ICU setting.
- Intravenous medications allow for precise control of blood pressure reduction, minimizing risks.
- Consultation with specialists is recommended for pediatricians managing these critical situations.
Abstract:
Children presenting with hypertension should be considered for emergency treatment when there is evidence of end-organ toxicity. Complications of extreme hypertension may be very serious, even life threatening, with the potential for life-long sequelae. Of greatest significance is damage to the central nervous system. Treatment of hypertensive emergencies should be directed toward the lowering of blood pressure enough to reduce toxicity, but not at a rate likely to cause hypoperfusion of vital organs. This blood pressure reduction should, in general, be carefully controlled in an intensive care unit, with attention to central nervous system, cardiac, and renal function. Intravenous agents are preferable under these circumstances, due to greater ease in modulating blood pressure. In the absence of specific contraindications, a continuous infusion of nicardipine or sodium nitroprusside is preferable. Intravenous labetalol by bolus injection, followed by continuous infusion, also may be used. Oral agents should be reserved for circumstances in which symptoms of end-organ toxicity are mild or absent. Since general pediatricians have limited experience with the treatment of hypertensive emergencies, consultation with physicians experienced in treating hypertensive emergencies is suggested when possible.
Related Concept Videos
Blood Pressure
The average BP in an adult is typically around 120/80 mmHg (millimeters of mercury). In this measurement, the numerator (120) indicates the systolic pressure, which is the pressure in the arteries during the contraction of the heart's ventricles as blood is expelled. The denominator (80) represents the diastolic...
Hypertension and Regulation of Blood Pressure
Blood Pressure
Blood Pressure Imbalances and Circulatory Shock
Blood Pressure: Hypertension and Hypotension
Normal blood pressure is 120/80 mm Hg. Elevated blood pressure is 120-129/under 80 mm Hg. Hypertension, warranting treatment at 130/80 mm Hg, is often asymptomatic and can lead to severe cardiovascular events, aneurysms, peripheral arterial disease, chronic renal disease, or cardiac...
Hypertension I: Introduction
Hypertension III: Clinical Manifestations and Diagnostic Studies

