[Histological grading and staging of IgA nephropathy]

The histological grading and staging (G-S system) is proposed in addition to the common histological diagnosis of IgA nephropathy, aiming the more precise understanding and appropriate therapeutic approach to the disease process. The histological grade (G) is estimated by the occurrence of acute glomerular and tubulointerstitial lesions, and histological staging (S) is evaluated by the increase of extra-cellular matrices (sclerosis) of the glomeruli and interstitial fibrosis. The evaluation of the G and S is expressed semiquantitatively for more helpful use in the clinical side. The G-S system may be beneficial for the management and therapeutic selection of patients of IgA nephropathy.