Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cardiovascular response to submaximal exercise in sustained microgravity

B E Shykoff1, L E Farhi, A J Olszowka

  • 1Department of Physiology, State University of New York at Buffalo 14214, USA. BShykoff@UBMEDC.Buffalo.EDU

Journal of Applied Physiology (Bethesda, Md. : 1985)
|July 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Application of quantitative and progressive exercise rehabilitation to patients with osteoarthritis of the knee.

Journal of back and musculoskeletal rehabilitation·2014
Same author

Energy cost of breathing at depth: effect of respiratory muscle training.

Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc·2012
Same author

Is the rate of whole-body nitrogen elimination influenced by exercise?

Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc·2012
Same author

Influence of exercise on nutritional requirements.

European journal of applied physiology·2010
Same author

Aerobic cost in elite female adolescent swimmers.

International journal of sports medicine·2009
Same author

Pulmonary effects of submerged exercise while breathing 140 kPa oxygen.

Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc·2009
Same journal

Change in Neutrophil-to-Lymphocyte Ratio after acute and chronic exercise: A Systematic Review and Meta-Analysis.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Ankylosing spondylitis and muscle sympathetic nerve activity: a case study.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Intracranial vasomotor and blood flow responses to light intensity aerobic exercise in young adults: a 4D flow MRI study.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Comparative assessments of the COSMED adaptive mixing chamber vs. breath-by-breath methods for oxygen uptake measurements in recreationally active adults.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Can we assess exercise metabolism from skin? Metabolomic profiles in skin dialysate collected during exercise.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Characterization of intracranial pressure variations in ventricular and subarachnoid spaces of the rat brain.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
See all related articles

Microgravity significantly alters cardiovascular function, increasing resting cardiac output and stroke volume while decreasing heart rate and blood pressure compared to erect posture. Exercise responses also differ, indicating unique physiological adaptations to spaceflight.

Area of Science:

  • Cardiovascular Physiology
  • Space Medicine
  • Human Physiology

Background:

  • Understanding cardiovascular adaptations to microgravity is crucial for astronaut health.
  • Previous simulations may not fully replicate the physiological effects of true microgravity.

Purpose of the Study:

  • To investigate cardiovascular responses at rest and during exercise in true microgravity.
  • To compare these responses to those observed in 1G (Earth gravity) conditions.

Main Methods:

  • Measurements of cardiac output (Q), heart rate (HR), blood pressure, and oxygen consumption (VO2) were taken in six subjects during spaceflight.
  • Exercise was performed at two intensity levels (30% and 60% of maximal VO2).
  • In-flight data were compared with control measurements in erect and supine positions on Earth.
Keywords:
NASA Discipline CardiopulmonaryNASA Discipline Number 00-00NASA Program FlightNon-NASA Center

Related Experiment Videos

Main Results:

  • Resting cardiac output was higher (126% of erect) and heart rate lower (81% of erect) in microgravity.
  • Resting stroke volume increased significantly in microgravity compared to erect and supine states.
  • The increase in cardiac output with workload was blunted in microgravity, and stroke volume decreased during exercise.

Conclusions:

  • True microgravity induces distinct cardiovascular adaptations compared to supine or simulated conditions.
  • These findings highlight the unique physiological challenges of spaceflight on the cardiovascular system.