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Complications associated with epidural steroid injections
1Department of Anesthesiology, Medical College of Wisconsin, Milwaukee 53226, USA.
Summary
Epidural steroid injections have few reported serious complications. Subarachnoid injections, especially multiple ones, have a few reported adverse events like meningitis and arachnoiditis.
Area of Science:
- Neurology
- Pain Management
- Medical Literature Review
Background:
- Concerns exist regarding epidural steroid injection (ESI) hazards.
- Objective data supporting these concerns is limited.
- This review examines adverse reactions reported for ESIs.
Purpose of the Study:
- To survey adverse reactions associated with epidural steroid injections.
- To assess the safety profile of epidural and subarachnoid steroid injections.
Main Methods:
- Literature review of peer-reviewed publications.
- Included reports on epidural/subarachnoid injections for sciatica.
- Surveyed adverse effects, review articles, and animal studies.
Main Results:
- Few serious complications reported for epidural steroid injections.
- Subarachnoid injections linked to aseptic/bacterial meningitis, arachnoiditis, and conus medullaris syndrome.
- Most subarachnoid complications followed multiple injections.
Conclusions:
- Serious complications from epidural steroid injections are rare.
- Subarachnoid injections have a few reported complications, often with prolonged, multiple injections.