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Patterns of phasic coronary collateral flow velocity in patients
R G Bach1, M J Kern, T J Donohue
1Department of Internal Medicine, St. Louis University Health Science Center, Missouri, USA.
Insights
Doppler signals from the flowire can quantify coronary collateral blood flow and its patterns. These signals help assess ischemia and left ventricular wall motion during balloon occlusion, aiding in understanding coronary collateral function.
Area of Science:
- Cardiovascular physiology
- Medical imaging
- Hemodynamics
Background:
- Assessing coronary collateral circulation is crucial for managing ischemic heart disease.
- Quantifying collateral blood flow provides insights into myocardial protection during coronary interventions.
- Current methods for collateral flow assessment have limitations in precision and real-time application.
Abstract:
Antegrade or retrograde collateral flow velocity Doppler signals, acquired with the flowire, permit the quantitation of collateral blood flow and its phasic patterns. The velocity spectra are easily visualized, and reproducible alterations during balloon occlusion may be directly related to coronary collateral flow-dependent variables of ischemia and left ventricular wall motion. The effects of pharmacologic stimulation on collateral flow remain under study.