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Double-blind comparison of zopiclone and flunitrazepam in elderly insomniacs with special focus on residual effects
O Dehlin1, B Rubin, A Rundgren
1Department of Internal Medicine, University Hospital, Lund, Sweden.
Current Medical Research and Opinion
|January 1, 1995
Abstract:
In a double-blind study of 102 patients with a mean age of 79 years, zopiclone was compared to flunitrazepam. The patients rated their sleep in a diary. There was no statistically significant difference between the relatively low dose of 5 mg zopiclone and 1 mg flunitrazepam for eleven out of the twelve variables measuring subjective sleep quality and quantity. There was no differences between the drugs as regards patients' feelings of being rested or alertness.