Related Experiment Video
Updated: Aug 16, 2026

Estimation of Urinary Nanocrystals in Humans using Calcium Fluorophore Labeling and Nanoparticle Tracking Analysis
Published on: February 9, 2021
[Nephrolithiasis in children]
J A Camacho Díaz1, J Casas Gómez, A Amat Barnés
1Sección de Nefrología, Hospital Infantil Sant Joan de Déu, Barcelona.
Insights
Pediatric urolithiasis affects 1 in 4,500 children, often linked to infections or metabolic issues. Early detection and treatment, like extracorporeal lithotripsy, are key for managing kidney stones in children.
Area of Science:
- Pediatric Nephrology
- Urology
- Medical Research
Abstract:
We reevaluated the medical records of 112 children with urolithiasis. The prevalence of this condition was 1/4.500 children admitted to our hospital. The mean age was 8.2 years and 54.4% of the afflicted patients were males. Fifty percent of the patients studied had a family history of urolithiasis. The two most frequent etiologies were urinary tract infections and metabolic disorders (hypercalciuria states, distal renal tubular acidosis and cystinuria). The etiology of the urolithiasis was unknown in 15% of our patients. The levels of magnesium and citrate, inhibitors of crystallization, were moderately low in some of the cases in which it was determined. Fifty percent of the children with urolithiasis showed urinary or renal complications. The extracorporeal lithotripsy was an effective treatment of urolithiasis in the patients in which it was performed. The recurrence rate was 8%. In one third of the urolithiasis associated with urinary infections and/or urinary tract malformations we found chronic pyelonephritis.
Related Concept Videos
Urinary Tract Calculi I: Introduction
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Urinary Tract Calculi III: Medical Management
Urinary Tract Calculi IV: Nutrition Therapy and Prevention
Urinary Tract Calculi V: Nursing Management
Urinary Tract Calculi VI: Surgical Management

