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Related Experiment Videos

Transplantation procedures in primary hyperoxaluria type 1

A Latta1, D E Müller-Wiefel, E Sturm

  • 1Universitätskinderklinik Eppendorf, Hamburg, Germany.

Clinical Nephrology
|July 1, 1996
PubMed
Summary

Primary hyperoxaluria type 1 (PH 1) in children can lead to early kidney failure. Isolated liver transplantation in young PH 1 patients can stabilize renal function and correct the metabolic defect, potentially delaying the need for kidney transplants.

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Area of Science:

  • Nephrology
  • Hepatology
  • Genetics

Background:

  • Primary hyperoxaluria type 1 (PH 1) frequently causes end-stage renal failure (ESRF) in children.
  • Treatment options for PH 1 in pediatric patients with chronic renal failure (CRF) are less established than for adults.