Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

On the solvent motion in electrophoretic systems

S V Ermakov1, M Y Zhukov, P G Righetti

  • 1Keldysh Institute of Applied Mathematics, Russian Academy of Sciences, Moscow, Russia.

Electrophoresis
|June 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Heterogeneity of storage proteins in maize.

Planta·2014
Same author

Minimizing the number of voltage sources and fluid reservoirs for electrokinetic valving in microfluidic devices.

Analytical chemistry·2011
Same author

Computer simulations of electrokinetic transport in microfabricated channel structures.

Analytical chemistry·2011
Same author

Preparative Aspects of Immobilized pH Gradients.

Methods in molecular biology (Clifton, N.J.)·2011
Same author

Gene Dosage in Capillary Electrophoresis : Prenatal Diagnosis of Down's Syndrome and Rh D/d Genotyping.

Methods in molecular medicine·2011
Same author

Capillary electrophoresis of peptides and proteins using isoelectric buffers.

Current protocols in protein science·2008

A corrected transport model for multicomponent mixtures in electric fields accounts for solvent motion, improving concentrated solution electrophoresis simulations. This approach ensures momentum balance and reveals fine effects in mixture evolution.

Area of Science:

  • Physical Chemistry
  • Chemical Engineering
  • Theoretical Chemistry

Background:

  • Electrophoresis simulations often simplify by neglecting solvent motion in multicomponent mixtures.
  • This simplification can lead to violations of momentum balance and inaccuracies, especially in concentrated solutions.
  • Existing models may lack consistency and fail to capture complex transport phenomena.

Purpose of the Study:

  • To propose a corrected model for transport processes in multicomponent mixtures under an electric field.
  • To enhance the consistency and accuracy of electrophoresis simulations for concentrated solutions.
  • To investigate the impact of solvent motion on mixture dynamics and conservation laws.

Main Methods:

  • Development of a corrected theoretical model that includes solvent motion.

Related Experiment Videos

  • Redefinition of mass fluxes to ensure automatic momentum balance.
  • Mathematical analysis of the model's equations for system evolution.

    • Main Results:

    • The proposed model ensures momentum balance, addressing a key limitation of previous models.
    • The new equations are more symmetric and simpler, facilitating analysis.
    • The model reveals subtle effects in mixture evolution and clarifies conservation laws like the Kohlrausch function.

    Conclusions:

    • Accounting for solvent motion is crucial for accurate modeling of multicomponent mixtures in electric fields.
    • The corrected model provides a more consistent and robust framework for electrophoresis simulations.
    • This work enhances understanding of electromigration phenomena and associated conservation principles.