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Premenstrual dysphoric disorder. An update

M Steiner1

  • 1McMaster University, Hamilton, Ontario, Canada.

General Hospital Psychiatry
|July 1, 1996
PubMed
Summary

Premenstrual dysphoric disorder (PMDD) diagnosis is aided by DSM-IV criteria and daily charting. Effective treatments include SSRIs or oophorectomy, targeting hormonal triggers or serotonin system sensitivity.

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Diagnosis and treatment of premenstrual dysphoric disorder: an update.

International clinical psychopharmacology·2001

Area of Science:

  • Reproductive psychiatry
  • Women's health
  • Mood disorders

Background:

  • Premenstrual dysphoric disorder (PMDD) is a severe mood disorder.
  • DSM-IV criteria aid in distinguishing PMDD from premenstrual syndrome (PMS).
  • PMDD significantly impacts women's lifestyle and daily functioning.

Purpose of the Study:

  • To outline diagnostic criteria for PMDD.
  • To discuss treatment options for PMDD.
  • To review the efficacy of various PMDD interventions.

Main Methods:

  • Utilizing DSM-IV diagnostic criteria.
  • Employing prospective daily charting for diagnosis confirmation.
  • Reviewing randomized placebo-controlled trials for treatment efficacy.

Main Results:

  • Selective serotonin reuptake inhibitors (SSRIs) demonstrate significant efficacy.
  • Oophorectomy (medical or surgical) is a highly effective treatment for severe PMDD.
  • Both eliminating hormonal triggers and modulating the serotonergic system are effective treatment strategies.

Conclusions:

  • Accurate diagnosis of PMDD is achievable through standardized criteria and charting.
  • A range of treatments exist, from lifestyle changes to medical and surgical interventions.
  • Pharmacological and surgical interventions targeting hormonal and neurochemical pathways offer effective PMDD management.

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