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Clarithromycin in treatment of early Lyme disease: a pilot study
R J Dattwyler1, E Grunwaldt, B J Luft
1Lyme Disease Center, State University of New York at Stony Brook 11794-8161, USA.
Antimicrobial Agents and Chemotherapy
|February 1, 1996
Abstract:
Forty-one patients with erythema migrans were enrolled in an open-labelled pilot study of oral clarithromycin, 500 mg twice daily for 21 days, for the treatment of early Lyme disease. Immediately posttherapy, pretreatment signs and symptoms resolved among 91% of the 33 evaluable patients. At 6 months, all 28 of the evaluable patients were well. Clarithromycin shows promise as an effective agent for the treatment of early Lyme disease and warrants further study.
