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Updated: Aug 26, 2026

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
Published on: October 12, 2018
Still's disease in a patient infected with human immunodeficiency virus type I
S Antinori1, S Rusconi, A L Ridolfo
1Clinica delle Malattie Infettive, Università degli Studi di Milano, Italy.
Abstract:
An autoreactive cellular immune response may be a part of HIV-1 infection. This autoimmune phenomenon also includes antibodies to collagen that can be associated to arthritis as a clinical condition. In this paper we describe a case of Still's disease in an adult HIV-1 infected patient who presented a marked amelioration in his condition after 15 days of steroid therapy, as well as an improvement of the arthritis. This rare autoimmune condition, which is connected with the disregulation of the immune system, must be taken into account in HIV-1 infected individuals who present with fever of unknown origin.
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