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Glutamate receptor subtypes localize to patches in the developing striatum
A Snyder-Keller1, L C Costantini
1Wadsworth Center for Laboratories and Research, New York State Department of Health, Albany 12201, USA. snykell@wadsworth.org
Brain Research. Developmental Brain Research
|July 20, 1996
Abstract:
The distribution of glutamate receptors in the developing striatum of the rat was studied using antibodies specific to AMPA and NMDA subtypes. Immunocytochemistry revealed a greater density of GluR1, GluR2/3, NMDAR1, and NMDAR2A/2B receptors in patches that matched the patches of substance P-immunoreactive neurons and dopaminergic terminals. GluR1-immunoreactive patches were the most distinctive and were present already at embryonic day 19.