Importance of microanalysis in understanding mechanism of transformation in active glassy biomaterials

This work deals with a method to study bioactive glassy materials used for repair of bone defects in order to understand the mechanism of the bioactivity and thus have its in vivo behavior optimized. The study of these materials takes into account their changes in morphology, by means of electron microscopy, after implantation in different animal models and evaluates the mechanism of the bioactivity through semi- and quantitative microanalytical evaluations in order to quantify the phenomenon of glass corrosion and the formation of a chemical bond with bone. Special preparations of glass granules before implantation were prepared to microanalytically study surfaces with different permeabilities.