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Related Experiment Videos

Akinetic mutism with bithalamic infarction. Neurophysiological correlates

P H van Domburg1, H J ten Donkelaar, S L Notermans

  • 1Department of Neurology, University Hospital Nijmegen, The Netherlands.

Journal of the Neurological Sciences
|July 1, 1996
PubMed
Summary
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Bilateral thalamic infarction caused akinetic mutism and selective downgaze palsy in a patient. This case highlights the thalamus's role in motor control and generalized epileptiform activity during reduced vigilance.

Area of Science:

  • Neuroscience
  • Neurology
  • Neurophysiology

Background:

  • Bilateral thalamic infarction can lead to complex neurological deficits.
  • The intralaminar thalamic nuclei are implicated in arousal and motor control.
  • Generalized epileptiform discharges are associated with reduced vigilance states.