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PICDI, a simple program for codon bias calculation
E Rodríguez-Belmonte1, M A Freire-Picos, A M Rodríguez-Torres
1Departamento de Biología Celular y Molecular, Facultad de Ciencias, La Coruña, Spain.
Molecular Biotechnology
|June 1, 1996
Abstract:
PICDI is a very simple program designed to calculate the Intrinsic Codon Deviation Index (ICDI). The program is available in Macintosh as well a PC format. Requirements for correct input of the sequences have been kept to a minimum and the analysis of sequences up to 2000 codons is very quick. The ICDI is very useful for estimation of codon bias of genes from species in which optimal codons are not known. The availability of a computer program for its calculation will increase its usefulness in the fields of Molecular Biology and Biotechnology.