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New bioactive marine steroids from the Okinawan soft coral Clavularia viridis
K Watanabe1, M Iwashima, K Iguchi
1Laboratory of Bioorganic Chemistry, School of Life Science, Tokyo University of Pharmacy, Japan.
Steroids
|July 1, 1996
Abstract:
Eight new marine steroids were isolated from the Okinawan soft coral Clavularia viridis Quoy and Gaimard. Their structures were determined based on spectroscopic analysis, chemical conversion, and X-ray crystallographic analysis. Steroids 5 and 6 showed growth inhibition activity toward HeLa S3 cells and human diploid cells in vitro.