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Controlled release dosage forms: from ground to space

P Colombo1, R Bettini, M T Peracchia

  • 1Dipartimento Farmaceutico, Università di Parma, Italy.

European Journal of Drug Metabolism and Pharmacokinetics
|April 1, 1996
PubMed
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Controlled drug release, a key pharmacy advance, is now central to drug delivery. This field optimizes drug efficacy, especially for new biotechnologies, by examining 25 years of research breakthroughs.

Area of Science:

  • Pharmacy
  • Biotechnology
  • Drug Delivery Science

Background:

  • Controlled drug release represents a significant advancement in pharmaceutical science.
  • Modern drug administration routes have integrated controlled release into the broader field of drug delivery.
  • Biotechnology advancements yield potent natural molecules, peptides, and proteins requiring sophisticated formulation strategies.

Purpose of the Study:

  • To review the evolution of drug delivery research over the past 25 years.
  • To identify pivotal breakthroughs in the field of drug delivery.
  • To highlight advancements in optimizing drug efficacy through advanced delivery systems.

Main Methods:

  • Literature review and analysis of drug delivery research publications from the last 25 years.

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  • Identification and synthesis of significant research contributions and technological advancements.
  • Examination of the impact of new drug administration routes and biotechnological products on drug delivery.
  • Main Results:

    • The field of drug delivery has expanded significantly, encompassing new administration routes and sophisticated formulations.
    • Biotechnology has enabled the use of complex molecules like peptides and proteins, necessitating advanced delivery solutions.
    • Key breakthroughs have focused on optimizing drug efficacy and patient compliance through controlled release mechanisms.

    Conclusions:

    • Drug delivery is a dynamic and critical discipline focused on maximizing therapeutic outcomes.
    • Continued research in drug delivery is essential for harnessing the potential of new biotechnological agents.
    • The past 25 years have witnessed transformative progress in controlled release and drug delivery technologies.