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Pharmacotherapy problems in the elderly

J F Steiner1

  • 1University of Wyoming, USA.

Journal of the American Pharmaceutical Association (Washington, D.C. : 1996)
|July 1, 1996
PubMed
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As the elderly population grows, pharmacists face more drug therapy challenges. Understanding physiologic aging is key to managing age-related drug effects and preventing adverse events in older adults.

Area of Science:

  • Geriatrics
  • Pharmacology
  • Internal Medicine

Background:

  • The aging population presents unique challenges for drug therapy management.
  • Age-related physiological changes significantly impact drug pharmacokinetics and pharmacodynamics.
  • Adverse drug events pose serious risks for the elderly, with over one in six Americans in this age group taking prescription medications.

Purpose of the Study:

  • To highlight the importance of considering age-related differences in drug therapy.
  • To emphasize the role of pharmacists in managing medication for older adults.
  • To underscore the need for individualized drug therapy plans in geriatrics.

Main Methods:

  • Review of current literature on aging, pharmacokinetics, and pharmacodynamics.

Related Experiment Videos

  • Analysis of age-related disease presentation and progression.
  • Examination of the impact of physiologic versus chronologic aging on drug responses.

    • Main Results:

    • Physiologic aging, not just chronological age, dictates differences in drug handling.
    • Individual variations in aging necessitate tailored drug therapy approaches.
    • Elderly patients are at high risk for serious adverse drug effects.

    Conclusions:

    • Pharmacists must be prepared to address complex drug therapy issues in the elderly.
    • Drug therapy plans require careful consideration of age-specific physiological changes.
    • Preventing adverse drug events is crucial for maintaining health in the aging population.