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Malignant chondroid syringoma

T B Sun1, H F Chien, S F Huang

  • 1Department of Surgery, National Taiwan University Hospital, Taipei, ROC.

Journal of the Formosan Medical Association = Taiwan Yi Zhi
|July 1, 1996
PubMed
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Malignant chondroid syringoma, a rare sweat gland tumor, can metastasize to bone. This case highlights the aggressive nature and poor prognosis of this foot tumor, even after radical treatment.

Area of Science:

  • Dermatology
  • Oncology
  • Orthopedic Surgery

Background:

  • Chondroid syringoma is a rare sweat gland tumor.
  • Malignant transformation of chondroid syringoma is exceptionally rare.
  • This case presents a unique instance of malignant chondroid syringoma with extensive bone metastases.

Observation:

  • An 18-year-old male presented with a recurrent plantar foot mass initially diagnosed as benign.
  • Over 10 years, the tumor recurred thrice, ultimately diagnosed as malignant chondroid syringoma.
  • Radiologic surveys revealed multiple bone metastases in the calcaneus, talus, and fibula.

Findings:

  • The patient underwent below-knee amputation and fibula removal.
  • Pelvic bone metastasis developed one year post-amputation.

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  • Widespread brain and bone metastases led to death 36 months after amputation.

    • Implications:

    • This case underscores the importance of vigilant monitoring and radical treatment for suspected malignant sweat gland tumors.
    • Early and aggressive management may be crucial for improving outcomes in rare aggressive tumors.
    • Further research into the pathogenesis and treatment of malignant chondroid syringoma is warranted.