Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Interaction between inclusions embedded in membranes

H Aranda-Espinoza1, A Berman, N Dan

  • 1Instituto de Físcia, Universidad Autónoma de San Luis Potosi, Mexico. helim@sbphy.physics.ucsb.edu

Biophysical Journal
|August 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

In response to "Patient perspectives in obstetric anaesthesia reports: invaluable learning for clinicians".

International journal of obstetric anesthesia·2025
Same author

A decade of obstetric anaesthetic case reports publications: a focused review.

International journal of obstetric anesthesia·2025
Same author

Occult myocardial injury is prevalent amongst elderly patients in the hospital-at-home setting. A retrospective analysis of 213 patients.

International journal of cardiology. Cardiovascular risk and prevention·2023
Same author

Actin protein inside DMPC GUVs and its mechanical response to AC electric fields.

Biochimica et biophysica acta. Biomembranes·2022
Same author

Characterization of novel polydiacetylene gel dosimeter for radiotherapy.

Biomedical physics & engineering express·2021
Same author

Irradiation with 365 nm and 405 nm wavelength shows differences in DNA damage of swine pancreatic islets.

PloS one·2020
Same journal

Enhanced-Sampling Simulations Reveal Distinct Intermediates in SARS-CoV-2 FSE Pseudoknot Interconversion.

Biophysical journal·2026
Same journal

Structure-based simulations of the full Flock House virus capsid reveal pathways and energetics of an infection-critical peptide externalization event.

Biophysical journal·2026
Same journal

Quantifying the Peripheral Surface Information Entropy from Conformational Ensembles of Globular Protein-Peptide Complexes.

Biophysical journal·2026
Same journal

Anisotropic unbinding and location-dependent hovering of a kinesin motor head over microtubule.

Biophysical journal·2026
Same journal

Kinesin-5/Cut7 C-terminal tail phosphorylation influence on motor regulation through multi-scale molecular modeling.

Biophysical journal·2026
Same journal

Dynamic conformations of fluorophores on self-labeling protein tags.

Biophysical journal·2026
See all related articles

Membrane properties influence how inclusions interact, with spacing affecting attraction/repulsion. Finite spontaneous curvature significantly alters these interactions, deviating from simple hard-core models.

Area of Science:

  • Biophysics
  • Soft Matter Physics
  • Materials Science

Background:

  • Membrane-bound inclusions can interact via deformations they induce in the lipid bilayer.
  • Understanding these interactions is crucial for processes like cell signaling and membrane organization.

Purpose of the Study:

  • To quantify the membrane-induced interaction between inclusions.
  • To investigate the role of membrane properties (stretching/bending moduli, spontaneous curvature) and inclusion characteristics (radius, spacing) on this interaction.

Main Methods:

  • Analytical calculations of membrane-induced forces based on elasticity theory.
  • Application of Ornstein-Zernike theory with Percus-Yevick closure to determine the radial distribution function of inclusions.

Related Experiment Videos

Main Results:

  • The interaction between inclusions is non-monotonic with spacing.
  • The energy minimum's location depends on spontaneous curvature and membrane perturbation decay length (determined by moduli).
  • Membrane perturbation energy scales with inclusion radius.

Conclusions:

  • Membrane deformation mediates inclusion interactions, which are sensitive to spontaneous curvature.
  • At zero spontaneous curvature, interactions resemble hard-core repulsion; finite spontaneous curvature leads to dramatically modified effective interactions.