Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Postinfectious chronic fatigue: a distinct syndrome?

D Buchwald1, J Umali, T Pearlman

  • 1Department of Medicine, University of Washington, Seattle, USA.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|August 1, 1996
PubMed
Summary

Chronic fatigue syndrome (CFS) often follows viral illness. Post-viral onset in chronic fatigue (CF) patients showed no unique clinical or biological markers, suggesting similar underlying factors for all CF cases.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

New Collaborative Research on Suicide Prevention, Practice, and Policy With American Indian and Alaska Native Communities Holds Promise for All Peoples.

Health promotion practice·2023
Same author

Sustaining suicide prevention programs in American Indian and Alaska Native communities and Tribal health centers.

Implementation research and practice·2022
Same author

The CODATwins Project: The Current Status and Recent Findings of COllaborative Project of Development of Anthropometrical Measures in Twins.

Twin research and human genetics : the official journal of the International Society for Twin Studies·2019
Same author

Obesity risk factors in American Indians and Alaska Natives: a systematic review.

Public health·2019
Same author

Transcriptional Signatures of Sleep Duration Discordance in Monozygotic Twins.

Sleep·2017
Same author

Extracorporeal life support (ECLS) for cardiopulmonary resuscitation (CPR) with pulmonary embolism in surgical patients - a case series.

Perfusion·2015

Area of Science:

  • Medical research
  • Immunology
  • Infectious diseases

Background:

  • Chronic fatigue syndrome (CFS) frequently presents after a viral infection, characterized by recurring flu-like symptoms.
  • Understanding the specific features differentiating post-viral onset in chronic fatigue (CF) is crucial for diagnosis and treatment.

Purpose of the Study:

  • To compare demographic, clinical, and laboratory findings in 717 chronic fatigue patients based on self-reported post-infectious onset.
  • To identify clinical and biological correlates of post-infectious onset.
  • To examine if these features differ in patients diagnosed with CFS.

Main Methods:

  • Comparative analysis of demographic, clinical (symptoms, functional status), and laboratory data (inflammation, viral markers).
  • Study included 717 patients with chronic fatigue (CF), with and without a self-reported post-infectious onset.

Related Experiment Videos

  • Statistical analysis to identify significant associations.

    • Main Results:

    • Subjective fever, chills, sore throat, lymphadenopathy, poorer functional status, and attributing illness to a physical cause were linked to post-infectious onset.
    • No significant differences in clinical or biological markers were found between CFS patients and the broader CF group.
    • Post-infectious onset did not correlate with a distinct pattern of psychosocial or biological abnormalities.

    Conclusions:

    • A post-infectious onset in chronic fatigue patients is associated with specific symptoms but not a unique biological or psychosocial profile.
    • The clinical and laboratory features of chronic fatigue syndrome (CFS) are similar to those of chronic fatigue (CF) in general.
    • These findings suggest that post-viral onset does not represent a distinct subtype of chronic fatigue based on the parameters studied.