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Non-contact, Label-free Monitoring of Cells and Extracellular Matrix using Raman Spectroscopy
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Published on: May 29, 2012

In situ analysis of the degree of polymerization of bone cement by using FT-Raman spectroscopy

I Rehman1, E J Harper, W Bonfield

  • 1Queen Mary and Westfield College, University of London, UK.

Biomaterials
|August 1, 1996
PubMed

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The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
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A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
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