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Development of ischemic colitis and scleroderma renal crisis following methylprednisolone pulse therapy for
Y Yamanishi1, S Yamana, S Ishioka
1Second Department of Internal Medicine, Hiroshima University School of Medicine.
Internal Medicine (Tokyo, Japan)
|July 1, 1996
Abstract:
We describe a patient with progressive systemic sclerosis who developed ischemic colitis and scleroderma renal crisis following steroid pulse therapy. The possible pathogenic mechanisms of ischemic colitis and scleroderma renal crisis development are discussed. We conclude that the administration of steroids in high doses, especially via steroid pulse therapy, should be undertaken with caution for progressive systemic sclerosis patients.